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anti mouse cd8 α  (Bio X Cell)


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    Structured Review

    Bio X Cell anti mouse cd8 α
    Anti Mouse Cd8 α, supplied by Bio X Cell, used in various techniques. Bioz Stars score: 96/100, based on 205 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/anti+cd8+%CE%B1/InVivoMAb+anti-mouse+CD8%CE%B2/pm42829916-411-4-19
    Average 96 stars, based on 205 article reviews
    anti mouse cd8 α - by Bioz Stars, 2026-10
    96/100 stars

    Images

    Related Articles

    other:

    Article Title: Anchoring of intratumorally administered cytokines to collagen safely potentiates systemic cancer immunotherapy
    Article Snippet: CD8 T cells, NK cells, or neutrophils were depleted with 400 μg of anti-CD8-α (2.43, BioXCell), anti-NK1.1 (PK136, BioXCell), or anti-Ly-6G (1A8, BioXCell) every four days.

    In Vivo:

    Article Title: cGAS and STING in Host Myeloid Cells Are Essential for Effective Cyclophosphamide Treatment of Advanced Breast Cancer
    Article Snippet: Mice were inoculated with 0.5 × 10 6 E0771 cells into the right fourth mammary fat pad on day 0 and then injected intraperitoneally (ip) with 150 mg/kg body weight CTX (Sigma-Aldrich) on day 21 and day 27, unless stated otherwise. .. For depletion of T cells in vivo, mice received an ip injection of 0.2 mg anti-CD4 (GK1.5, RRID:AB_1107636, BioXcell, Lebanon, NH, USA), anti-CD8 α (2.43, RRID:1125541, BioXcell), anti-CD4 plus anti-CD8 α , or isotype control antibody (Rat IgG2b, RRID:1107780, κ; BioXcell) 8 h before each CTX treatment. ..

    Article Title: Spatiotemporally engineered tumor-derived extracellular vesicle-based scaffold vaccine for personalized cancer immunotherapy.
    Article Snippet: Cells were subsequently assayed for IFN-γ by Elispot kit (Mabtech) and spot counts using instrument (BD Biosciences). .. In vivo T-cell depletion To deplete CD4+ T and CD8+ T cells, tumor-bearing mice were i.p. injected with anti-CD4 (clone GK1.5, BioXcell), anti-CD8-α (clone 2.43, BioXcell) or isotype (RatIgG1, BioXcell) antibodies. ..

    Injection:

    Article Title: cGAS and STING in Host Myeloid Cells Are Essential for Effective Cyclophosphamide Treatment of Advanced Breast Cancer
    Article Snippet: Mice were inoculated with 0.5 × 10 6 E0771 cells into the right fourth mammary fat pad on day 0 and then injected intraperitoneally (ip) with 150 mg/kg body weight CTX (Sigma-Aldrich) on day 21 and day 27, unless stated otherwise. .. For depletion of T cells in vivo, mice received an ip injection of 0.2 mg anti-CD4 (GK1.5, RRID:AB_1107636, BioXcell, Lebanon, NH, USA), anti-CD8 α (2.43, RRID:1125541, BioXcell), anti-CD4 plus anti-CD8 α , or isotype control antibody (Rat IgG2b, RRID:1107780, κ; BioXcell) 8 h before each CTX treatment. ..

    Article Title: Tumour sensitization via the extended intratumoural release of a STING agonist and camptothecin from a self-assembled hydrogel
    Article Snippet: To deplete NK cells, CD4 + T cells and CD8 + T cells, tumour-bearing mice were intraperitoneally injected with anti-NK1.1 (clone PK136, BioXCell), anti-CD4 (clone GK1.5, BioXCell), anti-CD8-α (clone 2.43, BioXCell) or isotype control (RatIgG1,BioXcell) antibodies at an initial dose of 400 mg 1 d before treatment, followed by 200 mg every 3 d. Depletion of CD8 + T cells, CD4 + T cells and NK cells was confirmed using flow cytometry analysis of peripheral blood mononuclear cells. .. To deplete NK cells, CD4 + T cells and CD8 + T cells, tumour-bearing mice were intraperitoneally injected with anti-NK1.1 (clone PK136, BioXCell), anti-CD4 (clone GK1.5, BioXCell), anti-CD8-α (clone 2.43, BioXCell) or isotype control (RatIgG1,BioXcell) antibodies at an initial dose of 400 mg 1 d before treatment, followed by 200 mg every 3 d. Depletion of CD8 + T cells, CD4 + T cells and NK cells was confirmed using flow cytometry analysis of peripheral blood mononuclear cells. ..

    Article Title: Spatiotemporally engineered tumor-derived extracellular vesicle-based scaffold vaccine for personalized cancer immunotherapy.
    Article Snippet: Cells were subsequently assayed for IFN-γ by Elispot kit (Mabtech) and spot counts using instrument (BD Biosciences). .. In vivo T-cell depletion To deplete CD4+ T and CD8+ T cells, tumor-bearing mice were i.p. injected with anti-CD4 (clone GK1.5, BioXcell), anti-CD8-α (clone 2.43, BioXcell) or isotype (RatIgG1, BioXcell) antibodies. ..

    Article Title: Supporting Information for Self-assembling paclitaxel-mediated stimulation of tumor-associated macrophages for postoperative treatment of glioblastoma
    Article Snippet: .. To deplete CD3+ T cells and CD8+ T cells, tumor-bearing mice were intraperitoneally injected with anti-CD3ε (clone 145-2C11, BioXCell) and anti-CD8-α (clone 2.43, BioXCell) or isotype control (RatIgG1, BioXcell) antibodies at an initial dose of 400 mg 1 d before treatment, followed by 200 mg every 3 d. Macrophages were depleted using 300 μg anti-CSF1R (clone AFS98, BioXCell) every other day. ..

    Article Title: Bifidobacterium pseudocatenulatum capsular exopolysaccharide enhances systemic anti-tumour immunity in pre-clinical breast cancer
    Article Snippet: For checkpoint immunotherapy experiments, tumour-bearing animals were intraperitoneally administered 20mg/kg anti-PD-1 mAb (Clone J43, BioXCell, New Hampshire, USA) or matched isotype control on days 7, 10, 13. .. Cellular depletions were induced through intraperitoneal injection of 400μg anti-CD8-α (clone 2.43, BioXCell) or matched isotype control mAb one day prior to Bifidobacterium administration (day 9), followed by 200μg injections thereafter on days 13, 16, and 19. ..

    Control:

    Article Title: cGAS and STING in Host Myeloid Cells Are Essential for Effective Cyclophosphamide Treatment of Advanced Breast Cancer
    Article Snippet: Mice were inoculated with 0.5 × 10 6 E0771 cells into the right fourth mammary fat pad on day 0 and then injected intraperitoneally (ip) with 150 mg/kg body weight CTX (Sigma-Aldrich) on day 21 and day 27, unless stated otherwise. .. For depletion of T cells in vivo, mice received an ip injection of 0.2 mg anti-CD4 (GK1.5, RRID:AB_1107636, BioXcell, Lebanon, NH, USA), anti-CD8 α (2.43, RRID:1125541, BioXcell), anti-CD4 plus anti-CD8 α , or isotype control antibody (Rat IgG2b, RRID:1107780, κ; BioXcell) 8 h before each CTX treatment. ..

    Article Title: Tumour sensitization via the extended intratumoural release of a STING agonist and camptothecin from a self-assembled hydrogel
    Article Snippet: To deplete NK cells, CD4 + T cells and CD8 + T cells, tumour-bearing mice were intraperitoneally injected with anti-NK1.1 (clone PK136, BioXCell), anti-CD4 (clone GK1.5, BioXCell), anti-CD8-α (clone 2.43, BioXCell) or isotype control (RatIgG1,BioXcell) antibodies at an initial dose of 400 mg 1 d before treatment, followed by 200 mg every 3 d. Depletion of CD8 + T cells, CD4 + T cells and NK cells was confirmed using flow cytometry analysis of peripheral blood mononuclear cells. .. To deplete NK cells, CD4 + T cells and CD8 + T cells, tumour-bearing mice were intraperitoneally injected with anti-NK1.1 (clone PK136, BioXCell), anti-CD4 (clone GK1.5, BioXCell), anti-CD8-α (clone 2.43, BioXCell) or isotype control (RatIgG1,BioXcell) antibodies at an initial dose of 400 mg 1 d before treatment, followed by 200 mg every 3 d. Depletion of CD8 + T cells, CD4 + T cells and NK cells was confirmed using flow cytometry analysis of peripheral blood mononuclear cells. ..

    Article Title: Supporting Information for Self-assembling paclitaxel-mediated stimulation of tumor-associated macrophages for postoperative treatment of glioblastoma
    Article Snippet: .. To deplete CD3+ T cells and CD8+ T cells, tumor-bearing mice were intraperitoneally injected with anti-CD3ε (clone 145-2C11, BioXCell) and anti-CD8-α (clone 2.43, BioXCell) or isotype control (RatIgG1, BioXcell) antibodies at an initial dose of 400 mg 1 d before treatment, followed by 200 mg every 3 d. Macrophages were depleted using 300 μg anti-CSF1R (clone AFS98, BioXCell) every other day. ..

    Article Title: Bifidobacterium pseudocatenulatum capsular exopolysaccharide enhances systemic anti-tumour immunity in pre-clinical breast cancer
    Article Snippet: For checkpoint immunotherapy experiments, tumour-bearing animals were intraperitoneally administered 20mg/kg anti-PD-1 mAb (Clone J43, BioXCell, New Hampshire, USA) or matched isotype control on days 7, 10, 13. .. Cellular depletions were induced through intraperitoneal injection of 400μg anti-CD8-α (clone 2.43, BioXCell) or matched isotype control mAb one day prior to Bifidobacterium administration (day 9), followed by 200μg injections thereafter on days 13, 16, and 19. ..

    Flow Cytometry:

    Article Title: Tumour sensitization via the extended intratumoural release of a STING agonist and camptothecin from a self-assembled hydrogel
    Article Snippet: To deplete NK cells, CD4 + T cells and CD8 + T cells, tumour-bearing mice were intraperitoneally injected with anti-NK1.1 (clone PK136, BioXCell), anti-CD4 (clone GK1.5, BioXCell), anti-CD8-α (clone 2.43, BioXCell) or isotype control (RatIgG1,BioXcell) antibodies at an initial dose of 400 mg 1 d before treatment, followed by 200 mg every 3 d. Depletion of CD8 + T cells, CD4 + T cells and NK cells was confirmed using flow cytometry analysis of peripheral blood mononuclear cells. .. To deplete NK cells, CD4 + T cells and CD8 + T cells, tumour-bearing mice were intraperitoneally injected with anti-NK1.1 (clone PK136, BioXCell), anti-CD4 (clone GK1.5, BioXCell), anti-CD8-α (clone 2.43, BioXCell) or isotype control (RatIgG1,BioXcell) antibodies at an initial dose of 400 mg 1 d before treatment, followed by 200 mg every 3 d. Depletion of CD8 + T cells, CD4 + T cells and NK cells was confirmed using flow cytometry analysis of peripheral blood mononuclear cells. ..



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    Chimerism in lymphoid tissue of allogeneic recipients transplanted with WT versus NOD1×2 −/− donor HSPCs. WT (solid line) or NOD1×2 −/− (dashed line) donor cells (both H-2K b ) detected by congenic antibody staining in bone marrow (Panel A), thymus (Panel B), lymph nodes (Panel C), spleen (Panel D) over time after the allogeneic HSPCs were transplanted into BALB/c (H-2K d ) recipient mice. (Panel E) shows no significant differences in CD3, CD4, <t>CD8,</t> B220, CD11c, F480, FoxP3/CD25+ or FoxP3/CD25− on peripheral donor cells over 20 wk in the recipients of WT (solid line) versus NOD1×2 −/− (dashed line) HSPCs. At each time point 5 WT and 5 NOD1×2 −/− chimeric mice were analyzed per group. Error bars are SD, * p < .05, ** p < .01.
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    Image Search Results


    Chimerism in lymphoid tissue of allogeneic recipients transplanted with WT versus NOD1×2 −/− donor HSPCs. WT (solid line) or NOD1×2 −/− (dashed line) donor cells (both H-2K b ) detected by congenic antibody staining in bone marrow (Panel A), thymus (Panel B), lymph nodes (Panel C), spleen (Panel D) over time after the allogeneic HSPCs were transplanted into BALB/c (H-2K d ) recipient mice. (Panel E) shows no significant differences in CD3, CD4, CD8, B220, CD11c, F480, FoxP3/CD25+ or FoxP3/CD25− on peripheral donor cells over 20 wk in the recipients of WT (solid line) versus NOD1×2 −/− (dashed line) HSPCs. At each time point 5 WT and 5 NOD1×2 −/− chimeric mice were analyzed per group. Error bars are SD, * p < .05, ** p < .01.

    Journal: Transplantation and cellular therapy

    Article Title: Simultaneous NOD1 and NOD2 Deletion in Hematopoietic Stem and Progenitor cells Promotes Long-Term Donor Chimerism

    doi: 10.1016/j.jtct.2026.01.031

    Figure Lengend Snippet: Chimerism in lymphoid tissue of allogeneic recipients transplanted with WT versus NOD1×2 −/− donor HSPCs. WT (solid line) or NOD1×2 −/− (dashed line) donor cells (both H-2K b ) detected by congenic antibody staining in bone marrow (Panel A), thymus (Panel B), lymph nodes (Panel C), spleen (Panel D) over time after the allogeneic HSPCs were transplanted into BALB/c (H-2K d ) recipient mice. (Panel E) shows no significant differences in CD3, CD4, CD8, B220, CD11c, F480, FoxP3/CD25+ or FoxP3/CD25− on peripheral donor cells over 20 wk in the recipients of WT (solid line) versus NOD1×2 −/− (dashed line) HSPCs. At each time point 5 WT and 5 NOD1×2 −/− chimeric mice were analyzed per group. Error bars are SD, * p < .05, ** p < .01.

    Article Snippet: For allogeneic transplants, recipient Balb/cByJ mice (H-2K d ) received sublethal irradiation with a single 3Gy dose using an X-ray source irradiator, followed 2 h later by i.p. injection with 1.5 mg of depleting anti-CD8 α antibody (clone 53.67, Bio X Cell, West Lebanon, NH).

    Techniques: Tissue, Staining